Saturday, January 11, 2014

Beeswax and Nonalcoholic fatty liver disease (NAFLD)

Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.

Beeswax is a natural wax produced in the bee hive of honey bees of the genus Apis, containg mainly esters of fatty acids and many types of long chain alcohols.

The benefits
Beeswax has been promoted as a health food for commercial profits in many parts of the world. Nonalcoholic fatty liver disease (NAFLD), as a result of abnormal function in fat accumulated in the liver. is associated with insulin resistance, liver fibrosis and cirrhosis, as a result of abnormal function in fat accumulated in the liver. D-002, a mixture of beeswax alcohols, in the study to test it efficacy in 50 NAFLD randomized to receive a placebo or D-002 (100 mg/day) for 24 weeks, D-002 exhibited a normal liver echo pattern on ultrasonography, improved symptoms and reduced insulin levels. Of that result, D002, may be considered as a potential agent in treating Nonalcoholic fatty liver disease (NAFLD) 

References
(1) Beeswax (Wikipedia)
(2) Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease by Illnait J, Rodríguez I, Mendoza S, Fernández Y, Mas R, Miranda M, Piñera J, Fernández JC, Mesa M, Fernández L, Carbajal D, Gámez R.(PubMed)

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