Hawthorn Fruit and Nonalcoholic fatty liver disease (NAFLD)

Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.
Hawthorn is a shrubs and trees of the genus Crataegus, belonging to the family Rosaceae, native to temperate regions of the Northern Hemisphere in Europe, Asia and North America. The herb has been used in traditional medicine to treat heart disease and symptoms of heart diseases such as irregular heartbeat, high blood pressure, chest pain, hardening of the arteries, etc., circulatory disorders and respiratory illnesses.
 
 Nonalcoholic fatty liver disease (NAFLD) is emerging as a widespread condition in US as approximate 30% of adult population are obese. Finding the natural treatments become for less or no side effects has become urgency in many scientific community including researchers in Universities. Alternative medicines for the treatment of NAFLD have been proven with many successful histories of controlling disease with no or less side effects, if compares to conventional treatment of the same. In a randomized controlled trials (RCTs) for the efficiency of traditional Chinese medicine (TCM) on the treatment of nonalcoholic fatty liver disease (NAFLD), Chinese herbal formulas have found to be effective in reducing the abnormality of alanine aminotransferase functions and fat accumulation in liver. Out of 246 kinds of Chinese herb, Hawthorn Fruit is found mostly in the list of many formulas. Of that reason, the herb may contain certain chemical constituents effectively in treatments of Nonalcoholic fatty liver disease (NAFLD).

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(1) Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD) by  Kim MS, Kung S, Grewal T, Roufogalis BD.(PubMed)
(2) Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis by Shi KQ, Fan YC, Liu WY, Li LF, Chen YP, Zheng MH.(PubMed)