Bayberry Juice and Non acoholic fatty liver disease(NALFD)

Bay berry is a species of Myrica gale, genus Myrica, belonging to  the family Myricaceae. Beside many nutrients, it also consists chemical constituents of Gallic acid, quercetin hexoside, quercetin deoxyhexoside, quercetin, anthocyanins, flavonols, and elllagitannins, etc.
Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption. 

The benefits
Bayberry juice is one  of favorite drink among Chinese citizens. the fruits has been cultivated over 2000 years in Chinese literature for foods and medical use. Because of it recently found  to contain certain chemicals with antioxidant effects, the fruits and its juice are being promoted as healthy products for commercial profits. In folk medicine, the fruit has been used in treating jaundice, painful and colitis, diarrhea, and nausea, etc.. Its main ingredient, anthocyanins, has been found to be effective in some studies for treating cardiovascular diseases and cancers. In a randomized, placebo-controlled, double-blind, crossover study of 44 participants (ages 18-25 y) given 250 mL of either bayberry juice or placebo twice daily for 4 wk, Bay berry juice is found to decrease inflammation and infection, liver cell apoptosis, and death of liver tissues as well as reduction of the risk of steatosis progreeion to cause NALFD. Of that results, researchers suggested that consumption of bayberry juice for a period of 4 wk can protect against NAFLD  and its juice may be a candidate for potential prevention and treatment of  Non acoholic fatty liver disease(NALFD).

The Side effects
1. Tannins found in bayberry may induce a drying effect on the skin and allergic effect in some patients
2. Bayberry may interactive with some prescription and non prescription medicine.
3. Etc.

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References
(1) Chemical composition of clarified bayberry (Myrica rubra Sieb. et Zucc.) juice sediment by Fang Z, Zhang M, Tao G, Sun Y, Sun J.(PubMed)(2) One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans.

Alvarez-Suarez JM¹, Giampieri F², Tulipani S³, Casoli T⁴, Di Stefano G⁵, González-Paramás AM⁶, Santos-Buelga C⁶, Busco F⁷, Quiles JL⁸, Cordero MD⁹, Bompadre S¹⁰, Mezzetti B¹¹, Battino M¹².(PubMed)

(3) Anthocyanins and their role in cancer prevention by Wang LS, Stoner GD.(PubMed)

(4) Effects of bayberry juice on inflammatory and apoptotic markers in young adults with features of non-alcoholic fatty liver disease by Guo H¹, Zhong R², Liu Y², Jiang X³, Tang X³, Li Z³, Xia M⁴, Ling W³.(PubMed)
(5) Anaphylaxis and generalized urticaria from eating Chinese bayberry fruit by Wang HY, Gao ZS, Yang ZW, Shao JX, Zhao XZ, Dai Y, Van Ree R.(PubMed)